Study on the sedative and analgesic effect of Intranasal dexmedetomidine combined with Intranasal Butorphanol during burn dressing changes

A study of dexmedetomidine combined with Butorphanol nasal spray on sedation, analgesia and inflammation of burn dressing change

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300071821

Enrollment

Unknown

Registered

2023-05-25

Start date

2023-06-01

Completion date

Unknown

Last updated

2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn injury

Interventions

Dexmedetomidine combined with Butorphanol nasal spray group.:Dexmedetomidine combined with butorphanol nasal spray was used before dressing change.

Butorphanol nasal spray group:Butorphanol nasal spray was used before dressing change.

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged between 20 and 60. 2. The burned area accounts for more than 30% of the total surface area. 3. Health physiological score ? to ?. 4. The cause of injury is burns or scalds. 5. The burn depth is second to third degree.

Exclusion criteria

Exclusion criteria: 1. They are pregnant. 2. Allergies to opioids. 3. History of vital organ disease. 4. combined with mental illness. 5. Mechanical ventilation is required.

Design outcomes

Primary

Measure	Time frame
Sedation score;Pain score;	—

Secondary

Measure	Time frame
Mean arterial pressure;Heart rate;Respiratory rate;Oxygen saturation;	—

Countries

China

Contacts

Public ContactXianchao Ding

The Affiliated hospital of Jiangsu University

robertding3324@sina.com+86 138 6244 6335

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026