Arteriosclerotic occlusion of lower extremity
Conditions
Interventions
Nerve block group NB group (If the patient has poor nerve block effect and the patient's body movement is seriously unable to cooperate with surgery, 1~3ug/kg of afentanil vein should be given for rem
MAC group (Afentanil was given 0.3~1ug/kg/min before the operation, and 1~3ug/kg was added once according to the patient's body movements during the operation. If respiratory depression occurs, suppor
Sponsors
Zhongshan Hospital ,Fudan University(Xiamen Branch)
Eligibility
Sex/Gender
All
Age
45 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Intracavitary interventional therapy for ASO patients in lower extremity is planned to be performed in Xiamen Hospital, Zhongshan Hospital Affiliated to Fudan University. 2. The estimated operation time is >= 60min. 3. Age >= 45 years old. 4. The anesthesia method was nerve block (iliac fascia combined with sciatic nerve block) or MAC. And at least one of the following risk factors 1. Age =60 years old 2. The patient presented clinical symptoms such as intermittent claudication, resting pain, and lower limb ulcer before surgery 3. hypertension requiring medical treatment 4. Patients with diabetes requiring medication or insulin therapy 5. Complicated with coronary atherosclerotic heart disease 6. Smoking history and not quit
Exclusion criteria
Exclusion criteria: 1. Severe coagulopathy accompanied by spontaneous bleeding or anesthesia is not suitable for regional block according to the attending physician's judgment of bleeding tendency 2. Preoperative acute attack of heart failure 3. Patients are at risk of infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting pain;Myocardial injury; | — |
Countries
China
Contacts
Public ContactLiuMannan
Zhongshan Hospital ,Fudan University (Xiamen Branch)
Outcome results
None listed