Knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age > 60 years old, regardless of gender; 2. Meet the diagnostic criteria for osteoarthritis in the Chinese Osteoarthritis Treatment Guidelines (2021 Edition); 3. Have a knee osteoarthritis more than 6 months; 4. Knee pain must be primarily due to tibiofemoral OA and not from patellofemoral OA; 5. X-ray imaging KL grade of affected knee >= 2; 6. Body mass index (BMI): 18.5 kg/m2 <= BMI < 28 kg/m2; 7. Willing and able to participate in this study; 8. Must give a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Absolute contraindication to exercise therapy; 2. Patients with inflammatory arthritis such as rheumatoid; 3. Joint instability caused by ligament injury; 4. Had intra-articular corticosteroid injections in the past 30 days; 5. All participants who previously underwent joint replacement-surgery; 6. Comorbidities that may influence the 3-month prognosis; 7. Patients with severe mental and psychological diseases; 8. Participation in exercise therapy for knee OA within the preceding 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiorespiratory fitness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of knee pain;Indicators of knee and quadriceps ultrasound;Muscle strength;Flexibility;Balance;Body composition;Health related quality of life;Safety indicators;Physical activity; | — |
Countries
China
Contacts
Xiangya Hospital, Central South University