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A randomized controlled study to compare outcomes of phacoemulsification plus goniosynechialysis vs phacoemulsification plus Ahmed glaucoma valve implantation in primary angle-closure glaucoma with moderate visual field defect

A randomized controlled study to compare outcomes of phacoemulsification plus goniosynechialysis vs phacoemulsification plus Ahmed glaucoma valve implantation in primary angle-closure glaucoma with moderate visual field defect

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071771
Enrollment
Unknown
Registered
2023-05-24
Start date
2023-06-01
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary glaucoma

Interventions

A:Phaco+IOL+AGV
B:Phaco+IOL+GSL

Sponsors

Beijing Tongren Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Voluntarily signed informed consent form for this study; 2. Chinese male or female patients aged 50-80 years old (including 50 and 80 years old); 3. Patients who met the diagnosis of primary angle closure glaucoma (PACG) with moderate visual field defect and received Phaco+IOL implantation combined with AGV implantation were included in this study. Patient who met the clinical diagnosis of primary angle closure glaucoma (PACG) with intermediate visual field defect and received Phaco+IOL implantation combined with GSL; 4. Combined cataract.

Exclusion criteria

Exclusion criteria: 1. Acute primary angle-closure (APAC) or PACG acute onset eye; 2. Unable or unwilling to sign consent forms, follow study procedures, or cooperate with eye examinations; 3. Secondary angle-closure glaucoma: Lens dislocation, uveitis, trauma, and neovascular glaucoma; 4. Previous surgery or anticipated need for additional surgery (except laser iridotomy) : previous cyclodestructive surgery, cataract surgery with or without intraocular lens implantation; Aphasic eyes; Expected need for other eye surgery or other eye operations, etc.; 5. Complicated with other eye diseases or abnormalities: including corneal abnormalities or corneal infection; Iridocorneal endothelial syndrome, anterior segment hypoplasia, nanophthalmos, high myopia (> 6.0D), uveitis, ocular tumors, ocular trauma, fundus lesions such as central retinal vein occlusion, central retinal artery occlusion, retinal detachment, etc.; 6. Pregnant or lactating women or with a history of serious systemic diseases: Patients with diabetes mellitus, hypertension (systolic blood pressure, >= 180mmHg or diastolic blood pressure, >= 100mmHg), advanced cardiac, renal, respiratory, or cancer; 7. For whom autoimmune conditions require long-term use of topical or systemic hormones or for whom hormone therapy is indicated.

Design outcomes

Primary

MeasureTime frame
Intraocular pressure, IOP;

Secondary

MeasureTime frame
complication;Best corrected visual acuity, BCVA;Visual sight;Cup to plate ratio, C/D;

Countries

China

Contacts

Public ContactZhigang Fan

Beijing Tongren Hospital, Capital Medical University

fanzhigang@mail.ccmu.edu+86 182 1834 2380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026