Adult patients scheduled surgery under general anesthesia
Conditions
Interventions
study group:deep blockade reversed with domestic sugammadex
control group:deep blockade reversed with Bridion
Sponsors
Department of Anesthesiology, Peking University First Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years, ASA I-III; 2. Patients undergoing elective surgery under general anesthesia and using rocuronium during operation.
Exclusion criteria
Exclusion criteria: 1. Patients with cirrhosis or liver failure and moderate renal dysfunction (glomerular filtration rate 40) or weight > 100 kg; 4. Suspected allergic patients to rocuronium and sugammadex; 5. Pregnant and lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time from the start of administration of sugammadex to recovery of the TOF ratio to 0.9; | — |
Secondary
| Measure | Time frame |
|---|---|
| TOFr values at 1min, 2min, 3min and 5min after Drug Administration;The ratio of TOFr to 0.9 within 3min;Blood pressure and heart rate within 5min of Drug Administration;Recover indoor adverse events;Incidence of respiratory complications 24 hours after surgery; | — |
Countries
China
Contacts
Public ContactZhiyu Geng
Department of Anesthesiology, Peking University First Hospital, Beijing, China
Outcome results
None listed