To investigate the effect of individualized transfusion strategy on the prognosis of elderly surgical patients
Conditions
Interventions
Sponsors
The Second Nanning People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Surgical patients, aged >= 60 years; 2. American Society of Anesthesiologists (ASA) class I-III; 3. The perioperative Hb was 60-100g / L.
Exclusion criteria
Exclusion criteria: 1. Serious hematological disease; 2. Hemoglobin oxygen carrying capacity; 3. Must undergo hypervolemic hemodilution; 4. Heart and blood vessel surgery, brain surgery, burn surgery; 5. History of acute stroke or mental illness; 6. Uncontrolled severe hypertension or hypotension (systolic blood pressure >= 160 mmHg, diastolic blood pressure >= 100 mmHg, systolic blood pressure = 1 month); 8. Has participated in other drug clinical trials as a subject in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transfusion rate;Volume of total blood transfusion;Incidence of postoperative delirium;Mortality;Incidence of serious postoperative complications;Arterial blood lactic acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hemoglobin value;Oxygen saturation of internal jugular vein;CD3+, CD4+, CD4+/CD8+ ratio;IL-1ß, IL-6, IL-8, CRP, TNF-a;Cortisol level; | — |
Countries
China
Contacts
Public ContactHuang Yanjuan
The Second Nanning People's Hospital
Outcome results
None listed