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Hypotensive anesthesia combined with tranexamic acid reduces perioperative blood loss during hip revision: a retrospective cohort study

Hypotensive anesthesia combined with tranexamic acid reduces perioperative blood loss during hip revision: a retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071738
Enrollment
Unknown
Registered
2023-05-24
Start date
2023-05-24
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

revision tha

Interventions

70-90 mmHg group:N/A
normal operation:N/A
below 70 mmHg:N/A

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adult patients receiving unilateral rTHA who underwent hip revision under hypotensive anesthesia and normal anesthesia at West China Hospital of Sichuan University from January 2010 to February 2023; 2. American Society of Anesthesiologists (ASA) Medical Conditions I-III; 3. Follow-up time exceeded 3 months.

Exclusion criteria

Exclusion criteria: Patients with contraindications to TXA include: 1. Coronary artery disease; 2. Renal failure (serum creatinine > 200 mmol/L, creatinine clearance 50s or prothrombin time > 5s).

Design outcomes

Primary

MeasureTime frame
hidden blood loss;Allogeneic blood transfusion volume;Incidence of symptomatic venous thromboembolism (VTE);Expression of inflammatory factors;Total postoperative hospital stay;Postoperative Pain;—

Countries

China

Contacts

Public ContactPengde Kang

West China Hospital of Sichuan University

kangpd@163.com+86 189 8060 1953

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026