Chronic obstructive pulmonary disease (COPD)
Conditions
Interventions
acupuncture group:Basic treatment plus acupuncture
placebo-acupuncture group:Basic treatment plus placebo acupuncture
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with stable COPD (in line with the diagnostic criteria published in the 2021 Global Initiative for Chronic Obstructive Pulmonary Disease(GOLD) and the guidelines for the diagnosis and treatment of chronic obstructive pulmonary disease (revised 2021)), and their condition has been stable without acute exacerbation in recent 4 weeks; 2. The severity of airflow restriction was classified as GOLD II-IV; 3. Participants are those aged between 40-80 years and no limitation of gender; 4. No history of infection or aggravation of respiratory symptoms, no drug changes and no edema symptoms within 3 months before the start of the study; 5. Patients who can walk independently; 6. Patients who have not undergone pulmonary rehabilitation in recent 6 months; 7. Good compliance, willing to cooperate with the research and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe dysfunction of cardiovascular and cerebrovascular system, nervous system, blood system, immune system, digestive system and thyroid, chronic liver and kidney insufficiency and malignant tumor; 2. Other concomitant active or clinically significant respiratory diseases that have a significant impact on the study; such as subjects with bronchial asthma, active tuberculosis, bronchiectasis, pulmonary interstitial diseases or other active lung diseases; 3. Those who use long-term oxygen therapy (oxygen therapy time > 15h / D) or mechanical ventilation; 4. Dissatisfied with blood pressure and blood glucose control; 5. Have a history of mental illness, mental retardation and mobility impairment; 6. Pregnant or lactating women; 7. Those who have participated in other clinical trials in recent 6 months or at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary lung function;symptom score;6 min walking test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Exacerbation frequency;Proportion of subjects with acute exacerbation;The Hospital Anxiety and Depression Scale;Inflammatory factors of induced sputum and serum;Functional connectivity of brain;Cognitive scale score; | — |
Countries
China
Contacts
Public ContactJuanjuan Fu
West China Hospital, Sichuan University
Outcome results
None listed