Disorders of Consciousness
Conditions
Interventions
Group ?:HD-tDCS and music stimulation were intervened simultaneously
Group ?:HD-tDCS
Group ?:Music combined with sham HD-tDCS stimulation group
Sponsors
Shenzhen Second people‘s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) The subject's family agrees that the patient joins the study and signs the informed consent form; (2) The clinical diagnosis was impaired consciousness, and the diagnostic criteria were based on the criteria of the American Society of Neurology and Rehabilitation Medicine in 2002, and the revised version of the coma recovery scale-revised (CRS-R) was assessed as VS/UWS or MCS according to the revised version of the coma recovery scale-revised (CRS-R) one week before stimulation; (3) Onset time= 28 days; (4) Age 18~80 years old; (5) There was no history of hearing loss, showing normal or slightly delayed mid-latency auditory evoked potential, and somatosensory evoked potential obtained by stimulation of the median nerve showed the presence of primary somatosensory cortical potential (N20); (6) Have not received tDCS treatment within 3 months prior to the study to avoid spontaneous recovery.
Exclusion criteria
Exclusion criteria: (1) the presence of pacemakers, aneurysm clips, neurostimulators or metal brain implants (according to safety standards for human transcranial electrical stimulation); (2) neuroimaging evidence of focal lesions of left-sided DLPFC; (3) serious medical conditions that may affect clinical diagnosis and EEG assessment (e.g., presence of severe cardiopulmonary disease, kidney disease, or liver disease); (4) Previous history of epilepsy, psychiatric or neurodegenerative diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG;CRS-R;fMRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| GOS;DRS; | — |
Countries
China
Contacts
Public ContactYulong Wang
Shenzhen Second People's Hospital
Outcome results
None listed