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MEC90 and analgesic effects of lidocaine for the breakthrough pain during labor after epidural analgesia

MEC90 and analgesic effects of lidocaine for the breakthrough pain during labor after epidural analgesia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071657
Enrollment
Unknown
Registered
2023-05-22
Start date
2023-05-22
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor pain

Interventions

Group A:0.08% Ropivacaine +0.4ug/ml Sufentanil 10ml epidural injection
Group B:MEC90 Lidocaine 10ml epidural injection
Group S:In the case of breakthough pain (VAS=50mm), 10 ml of sequential concentration lidocaine was artificially added to the epidural, and the pain of two consecutive contractions was relieved after

Sponsors

Fujian Provincial Hospital South Branch
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: From May 2023 to February 2024, a total of 120 women, ASA I or II grade, single fetus, full-term first-time delivery, aged 18-35 years old, met the indications for vaginal delivery, and cervical dilation =6cm, were required to receive labor analgesia in the obstetrics department of our hospital.

Exclusion criteria

Exclusion criteria: (1) Patients with intravertebral analgesia contraindications; (2) there was no breakthough pain during labor; (3) Allergic to analgesic drugs; (4) Patients with severe hypertension and severe heart, liver and kidney insufficiency; (5) conversion to cesarean section during analgesia.

Design outcomes

Primary

MeasureTime frame
Duration of pain relief from two consecutive contractions after the breakthrough pain management;Positive response to pain relief;

Secondary

MeasureTime frame
Mean arterial pressure;Length of first stage of labor;Heart rate;Maternal satisfaction;Dosing frequency;Newborn weight;

Countries

China

Contacts

Public ContactSu Yongjun

Fujian Provincial Hospital South Branch

175670378@qq.com+86 150 0599 2912

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026