Preadministration of low-dose ephedrine alleviates hemodynamic inhibition induced by propofol in elderly patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300071606

Enrollment

Unknown

Registered

2023-05-19

Start date

2023-05-21

Completion date

Unknown

Last updated

2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pharmacodynamics

Interventions

treatment group:Preadministration of low-dose ephedrine

Control group:Normal saline

Eligibility

Sex/Gender

All

Age

65 Years to 98 Years

Inclusion criteria

Inclusion criteria: ASAI-? elective surgery patients aged 65 years or older were selected; 180 cases (60 cases aged 65-74 years; 60 patients aged 75-84 years; 60 patients aged 85 years or older).

Exclusion criteria

Exclusion criteria: Patients with severe heart, liver, lung, or renal insufficiency and patients with uncontrolled hypertension were excluded from this study.

Design outcomes

Primary

Measure	Time frame
Blood pressure and heart rate;	—

Secondary

Measure	Time frame
Dose of vasoactive drugs such as ephedrine and atropine;	—

Countries

China

Contacts

Public ContactJINCHAO SONG

Shidong Hospital of Shanghai

sjch2013@163.com+86 131 6700 0520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026