Acute brain injury
Conditions
Interventions
APRV Group:Use airway pressure release ventilation mode to support the patient
PCV Group:Use assist/ control mode to support the patient
Sponsors
The First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age range from 18 to 75 years old, gender is not limited; ; 2. Invasive mechanical ventilation is required postoperatively in ICU; 3. Acute brain injury including severe ischemia stroke, ICH, SAH and TBI
Exclusion criteria
Exclusion criteria: 1. Pregnant women; 2. The patient's circulation is unstable, with systolic blood pressure 130bpm; 3. PaO2/FiO2<100 after surgery; 4. Chronic liver disease and renal disease; 5. Refuse to be enrolled.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation;30-day mRS;Barotrauma;PaO2/FiO2;Indicators of respiratory mechanics;Noninvasive intracranial pressure monitoring;CPIS;Acute Physiology and Chronic Health Evaluation score;Sequential Organ Failure Assessment score;Tracheostomy rate; | — |
Countries
China
Contacts
Public ContactWu Wen
The First College of Clinical Medical Science, China Three Gorges University, Yichang Central People's Hospital
Outcome results
None listed