Gynecological laparoscopic surgery
Conditions
Interventions
Intervention group:Nox-guided remifentanil in laparoscopic surgery:
standard of care:Remifentanil was used according to clinical experience
Sponsors
First People's Hospital of Changde city
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age greater than 18 but less than 65 years old; 2. ASA level I to III; 3. Selective laparoscopic appendage and/or hysterectomy surgery; 4. Expected surgical duration>1 hour; 5. Sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. NOX monitoring cannot be carried out (such as damage to the forehead skin); 2. History of central nervous system diseases and mental illnesses; 3. Preoperative use of chronic opioid drugs (defined as taking 60 milligrams of morphine equivalent daily for the past 3 months and lasting for more than 1 week); 4. Body mass index exceeding 28 kg/m2; 5. Patients who have implanted pacemakers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The consumption of remifentanil during the surgery;Postoperative opioid consumption (morphine equivalents) in the PACU; | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of time for the intraoperative NOX more than 50;The number of patients with hemodynamic instability;Wake-up time (Time between the end of remifentanil and extubation);NRS scores at rest and cough within 30 minutes of extubation and 24 hours, nausea and vomiting score and number of patients reporting respiratory depression (an oxygen saturation below 90%) and pruritus will also be collected within 30 minutes after extubation and 24 hours;The time it takes to request analgesia for the first time;Nonsteroidal anti-inflammatory drug (NSAID) consumption within 24 hours after surgery; | — |
Countries
China
Contacts
Public ContactXiaoting Shi
First People's Hospital of Changde city
Outcome results
None listed