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Study on the correlation and mechanism between periodontitis and inflammatory bowel disease

Study on the correlation and mechanism between periodontitis and inflammatory bowel disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071586
Enrollment
Unknown
Registered
2023-05-18
Start date
2023-05-25
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periodontitis

Interventions

Experimental group:None
Control group:None

Sponsors

Shanghai Dental Tissue Restoration and Regeneration Engineering Technology Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 39 Years

Inclusion criteria

Inclusion criteria: Inflammatory bowel disease Inclusion criteria 1) Clinical/endoscopic/historical diagnosis of inflammatory bowel disease; 2) No history of diabetes, hypertension or hyperlipidemia; 3) Age: 16-39 years old; 4) No probiotics in the past 2 weeks; 5) No antibiotics in the past 3 months; 6) No surgical history. Healthy control group Inclusion criteria 1) No history of diabetes, hypertension or hyperlipidemia; 2) Age: 16-39 years old; 3) No probiotics in the past 2 weeks; 4) No antibiotics in the past 3 months; 5) No surgical history;

Exclusion criteria

Exclusion criteria: Inflammatory bowel disease Exclusion criteria: 1) Have a history of other systemic diseases; 2) Antibiotics were taken within 6 months before enrollment; 3) Smoking patients; 4) The researcher predicted poor compliance; 5) Women are pregnant, nursing or taking contraceptives. Healthy control group Exclusion criteria: 1) Have a history of other systemic diseases; 2) Antibiotics were taken within 6 months before enrollment; 3) Smoking patients; 4) The researcher predicted poor compliance; 5) Women are pregnant, nursing or taking contraceptives.

Design outcomes

Primary

MeasureTime frame
Clinical attachment level;Probing depth PD;Bleeding on probing;Plaque index;Gingival index;Saliva microbiota;

Countries

China

Contacts

Public ContactYan xiangzhen

Tongji University Affiliated Stomatological Hospital

xiangzhenyan03@163.com+86 177 1791 3175

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026