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To study the susceptibility gene detection and molecular typing of chronic obstructive pulmonary disease (COPD)

To study the susceptibility gene detection and molecular typing of chronic obstructive pulmonary disease (COPD)

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071579
Enrollment
Unknown
Registered
2023-05-18
Start date
2021-02-11
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

COPD group :None
Healthy control group:None

Sponsors

General Hospital of Ningxia Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Diagnostic criteria: chronic cough, sputum, dyspnea, and/or a history of exposure to COPD risk factors. Pulmonary function tests indicated that FEV1/FVC < 0.70 after bronchodilator application; (2) Stable COPD; (3) The age group of Han nationality is more than 40 years old.

Exclusion criteria

Exclusion criteria: (1) Acute exacerbation of COPD occurred within 2 weeks; (2) Complicated with other pulmonary diseases: pulmonary interstitial diseases, active pulmonary tuberculosis, pleural effusion, lung tumors, pulmonary resection, etc.; (3) Complicated with cardiac insufficiency, severe liver and kidney dysfunction, mental and cognitive dysfunction; (4) poor dependence.

Design outcomes

Primary

MeasureTime frame
FAM13A SNPs;HHIP SNPs;CHRNA3 SNPs;

Secondary

MeasureTime frame
MMP-9;MMP-12;IL-17;IL-18;Lung function test;CT of the chest;

Countries

China

Contacts

Public ContactJin Zhang

General Hospital of Ningxia Medical University

jinzhangnew@hotmail.com+86 139 9508 2493

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026