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Hypotensive anesthesia combined with tranexamic acid reduces perioperative blood loss in total hip replacement DAA: a retrospective cohort study·

Hypotensive anesthesia combined with tranexamic acid reduces perioperative blood loss in total hip replacement DAA: a retrospective cohort study·

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071566
Enrollment
Unknown
Registered
2023-05-18
Start date
2023-05-19
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

THA

Interventions

Those with blood pressure less than 70mmhg:None
Those with blood pressure on 70-90mmhg:None

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (i) Adult patients receiving primary unilateral DAA who underwent hip revision under hypotensive anesthesia and normal anesthesia at West China Hospital of Sichuan University from January 2010 to February 2023; (ii) American Society of Anesthesiologists (ASA) Medical Conditions I-III; (iii) Follow-up time exceeded 3 months.

Exclusion criteria

Exclusion criteria: Patients with contraindications to TXA include (1) coronary artery disease, (2) renal failure (serum creatinine > 200 mmol/L, creatinine clearance 5s).

Design outcomes

Primary

MeasureTime frame
Perioperative blood loss;—

Secondary

MeasureTime frame
Postoperative Pain;—

Countries

China

Contacts

Public ContactKang pengde

West China Hospital, Sichuan University

kangpd@163.com+86 189 8060 1953

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026