Excessive daytime sleepiness
Conditions
Interventions
Experimental group:true tDCS
Observation group:collecting cortical function data
Sponsors
Tangdu Hospital, Fourth Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria of OSA in adults in ICSD-3, and meet both A and B or C. A. At least one of the following occurs: ?. Sleepy, non-restorative sleep, fatigue, insomnia; ?. Hold awake, gasp, suffocate; ?. Snoring and/or interrupted breathing observed by bed partners or others during sleep; ?. Diagnosis of hypertension, mood disorders, cognitive dysfunction, coronary heart disease, stroke, congestive heart failure, atrial fibrillation, type 2 diabetes; B. Obstructive respiratory events (obstructive or combined apnea, hypopnea, respiratory effort-related arousal) =5 times per hour through PSG monitoring or home monitoring; C. PSG or sleep-breathing home monitoring confirmation: obstructive respiratory events (apnea, hypopnea, respiratory effort-related arousal) =15 / hour by PSG or home monitoring. 2), ESS=10 points; 3), right hand; 4) Age range 18-65. 5) Years of education =12 years, education level of junior high school or above; 6) Never received PAP or surgery for OSA disease; 7) Sign informed consent.
Exclusion criteria
Exclusion criteria: 1) Other severe neuropsychiatric diseases or brain structural abnormalities in the past; 2) History of serious systemic diseases such as heart, lung, liver, kidney and thyroid, history of infectious diseases such as syphilis and AIDS, history of severe brain trauma and surgery, history of heavy alcoholism, long-term use of benzodiazepines and drug addiction; 3) Metal foreign bodies in the body, including stents, DBS treatment devices, cardiac pacemakers, cochlear implants, etc.; 4) Can not cooperate with the inspection operation; 5) Local skin diseases on the scalp; 5) The physician assessed other conditions that were not suitable for study participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stanford Sleepiness Scale (SSS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Epworth Sleepiness Scale(ESS);Karolinska Sleepiness Scale(KSS);Insomnia Severity Indeex(ISI));Pittsburgh?sleep quality index(PSQI);Hamilton Depression Scale(HAMD);Hamilton Anxiety Scale(HAMA);Mini-Mental State Examination(MMSE);Montreal Cognitive Assessment(MoCA);Morningness-Eveningness Questionnaire(MEQ);Right-handed questionnaire;actiwatch;polysomnography;PVT-ERP;corsi-ERP;rest motor threshold(rMT);active motor threshold(aMT);cortical silence period(CSP);input-output curve(I-O curve);intracortical inhibition(ICI);intracortical facilitation(ICF));Motion-evoked potentials(MEP);electroencephalogram(EEG); | — |
Countries
China
Contacts
Public Contactcheng jinxiang
Tangdu Hospital, Fourth Military Medical University
Outcome results
None listed