FindTrial
Sign In

Study of anti-Kawasaki disease effect and mechanism of active peptide ASRP2 by serum multiomics technique

The role and mechanism of active peptide ASRP2 in regulating NLRP3/ GSDMD-mediated pyrodeath in vascular inflammatory injury in Kawasaki disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071554
Enrollment
Unknown
Registered
2023-05-18
Start date
2023-05-19
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kawasaki disease

Interventions

KD group:none
normal group:none

Sponsors

Chengdu Women's and Children's Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: ? Healthy children and children whose first diagnosis was KD within 5 to 8 days were selected as healthy control group and Kawasaki disease group, respectively. According to the 5th Revision of the Kawasaki Disease Research Council Diagnostic Guidelines, all KD patients included in the study were rigorously diagnosed. ? The subject or his guardian will sign the informed consent voluntarily.

Exclusion criteria

Exclusion criteria: Exclude immune diseases, metabolic diseases, inflammatory diseases, severe liver and kidney diseases, and other heart diseases. Blood samples, echocardiography and clinical laboratory indicators were collected in all KD children before receiving IVIG and anticoagulant therapy.

Design outcomes

Primary

MeasureTime frame
peptide;—

Countries

China

Contacts

Public ContactShasha Xing

Chengdu Women's and Children's Central Hospital

xingshasha1230@126.com+86 173 1898 3677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026