Effect and efficiency of microneedle radiofrequency in the treatment of periorbital wrinkles: a prospective, randomized, split-face study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300071523

Enrollment

Unknown

Registered

2023-05-17

Start date

2023-02-01

Completion date

Unknown

Last updated

2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wrinkle

Interventions

long pulse-width group :long pulse-width microneedle radiofrequency

short pulse-width group:short pulse-width microneedle radiofrequency

Eligibility

Sex/Gender

All

Age

25 Years to 65 Years

Inclusion criteria

Inclusion criteria: periorbital wrinkles, Fitzpatrick score>3, 25-65 years old, male/female; haven't got any treatment of periorbital wrinkles in the last year; written informed consents were taken from all patients or their guardians; accept the randomized, split-face design and follow-up schedule.

Exclusion criteria

Exclusion criteria: pregnancy or plan for pregnancy ; allergic to local anesthetic; current facial infection or wound; patients with serious organic or mental illness; is participating other clinical trials; plan to accept laser/injection/surgery in periorbital area within 1 year; other conditions unsuitable for this research

Design outcomes

Primary

Measure	Time frame
The Fitzpatrick Wrinkle Classification System,FWCS;	—

Secondary

Measure	Time frame
Lemperle periorbital wrinkle scale;Global Aesthetic Improvement Score, GAIS;area of the periorbital wrinkle;	—

Countries

China

Contacts

Public ContactYali Yang

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

ky7812@126.com+86 158 0189 1767

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026