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An exploratory study on establishing the minimum clinical significance difference of speech, articulation and cognitive function related assessment scale after acquired brain injury

An exploratory study on establishing the minimum clinical significance difference of speech, articulation and cognitive function related assessment scale after acquired brain injury

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071519
Enrollment
Unknown
Registered
2023-05-17
Start date
2023-06-01
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acquired brain injury

Interventions

Case series:none

Sponsors

Huashan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Combined with clinical manifestations and head CT and/or MRI, it was diagnosed as acquired brain injury; (2) Age Above 18 years old, regardless of gender; (3) With clear mind and stable condition, it can cooperate with speech, articulation and cognitive assessment; (4) There are speech (AQ value of WAB<93.8 points), articulation (= 26 items in FDA are rated as grade a) or cognitive impairment (NLCA<70); (5) Volunteer to participate in the study and cooperate with various assessments; (6) The informed consent form has been signed.

Exclusion criteria

Exclusion criteria: (1) Diagnosed as perinatal, developmental and/or degenerative brain disease; (2) With severe heart, lung Liver and kidney diseases and malignant tumors; (3) Before the onset of this disease, there were speech, articulation, cognitive impairment or speech, articulation, cognitive impairment caused by other reasons.

Design outcomes

Primary

MeasureTime frame
Western Aphasia Battery,WAB;The Non-language-based Cognitive Assessment,NLCA;Frenchay;clock drawing test, CDT;

Countries

China

Contacts

Public ContactZhang Yuqian

Huashan Hospital, Fudan University

19111220005@fudan.edu.cn+86 173 1714 9920

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026