Mild Cognitive Impairment (MCI)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.The subjects were screened according to the 2018 Chinese guidelines for the diagnosis and treatment of dementia and cognitive impairment; 2. Be over 60 years old; 3. No severe hearing, speech and comprehension impairment, can complete various cognitive assessments and fNIRS experiments; 4. No serious underlying diseases, especially cardiovascular diseases; 5. No history of psychiatric diseases and psychotropic drugs; 6. No history of substance addiction (drugs, alcohol); 7. Informed consent and voluntary signing of the Informed Consent Form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiovascular, cerebrovascular, liver, kidney, malignant tumors, hematological diseases, and mental diseases; 2. Patients with Severe disturbance of consciousness, dementia or suffering from certain diseases that affect the evaluation of curative effect, such as aphasia, visual and hearing impairment; 3. Those who are unable or unwilling to cooperate with rehabilitation assessment; 4. Cognitive disorders, mental disorders, long-term alcohol abuse or a history of illegal drug use; 5. Women who are pregnant or breastfeeding, or have pregnancy plans in next six months; 6. Those who are participating in other clinical trials or have participated in other clinical trials in the past 3 months; 7. Patients judged by the investigator to be unsuitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional near - infrared spectroscopy, fNIRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment,MoCA;Mini-Mental State Examination,MMSE;TMTA;TMTB;DSF;DSB;IADL;Pitsburgh sleep quality indexs,PSQI; | — |
Countries
China
Contacts
Hubei Provincial Directly Administered Hospital