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Neurobiological markers of mild cognitive impairment in the elderly: based on fNIRS technology

Neurobiological markers of mild cognitive impairment in the elderly: based on fNIRS technology

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071516
Enrollment
Unknown
Registered
2023-05-17
Start date
2023-06-01
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment (MCI)

Interventions

Normal group:None
Patient group:None

Sponsors

Hubei Provincial Directly Administered Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.The subjects were screened according to the 2018 Chinese guidelines for the diagnosis and treatment of dementia and cognitive impairment; 2. Be over 60 years old; 3. No severe hearing, speech and comprehension impairment, can complete various cognitive assessments and fNIRS experiments; 4. No serious underlying diseases, especially cardiovascular diseases; 5. No history of psychiatric diseases and psychotropic drugs; 6. No history of substance addiction (drugs, alcohol); 7. Informed consent and voluntary signing of the Informed Consent Form.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiovascular, cerebrovascular, liver, kidney, malignant tumors, hematological diseases, and mental diseases; 2. Patients with Severe disturbance of consciousness, dementia or suffering from certain diseases that affect the evaluation of curative effect, such as aphasia, visual and hearing impairment; 3. Those who are unable or unwilling to cooperate with rehabilitation assessment; 4. Cognitive disorders, mental disorders, long-term alcohol abuse or a history of illegal drug use; 5. Women who are pregnant or breastfeeding, or have pregnancy plans in next six months; 6. Those who are participating in other clinical trials or have participated in other clinical trials in the past 3 months; 7. Patients judged by the investigator to be unsuitable to participate in this trial.

Design outcomes

Primary

MeasureTime frame
functional near - infrared spectroscopy, fNIRS;

Secondary

MeasureTime frame
Montreal Cognitive Assessment,MoCA;Mini-Mental State Examination,MMSE;TMTA;TMTB;DSF;DSB;IADL;Pitsburgh sleep quality indexs,PSQI;

Countries

China

Contacts

Public ContactXia Wenguang

Hubei Provincial Directly Administered Hospital

docxwg@163.com+86 27 8723 7160

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026