melasma
Conditions
Interventions
Experimental group:fractional microneedle radiofrequency
Sponsors
Southern Medical University, Dermatology Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1) Stable stage of melamsa (not in inflammatory erythema period); 2) Aged 18-50 years; 3) Agree to follow the experimental treatment plan and visit plan, voluntarily enroll, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Any uncontrollable serious or potentially affecting clinical system disease history/surgical history for treatment and effectiveness evaluation, such as circulatory system, nervous system, hematological system, immune system, mental system diseases, etc; 2) Receiving other facial rejuvenation treatments during the treatment period; 3) Exposure to sunlight without protective measures during treatment; 4) Have a history of malignant tumors; 5) The patient has uncontrollable hypertension (blood pressure above 140 mmHg/90 mmHg), or a history of hypotension (blood pressure below 90 mmHg/60 mmHg); 6) Recent history (within 3 months prior to screening) of surgery or planning to undergo major surgery during the trial period; 7) Individuals who have participated or are currently participating in clinical trials of other intervention drugs or medical devices within the first 3 months of screening; 8) Three months prior to screening, other medications such as phototherapy, oral tranexamic acid, glutathione, oral contraceptives, isotretinoic acid, minocycline, etc. that affect the condition of melasma or have photosensitive properties were received; 9) History of drug abuse, drug use, or alcohol dependence prior to screening; 10)The researcher believes that the subject has other situations that may affect compliance or be unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| modified melasma area and severity index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Subject self-evaluation;VISIA image analysis system; | — |
Countries
China
Contacts
Public ContactLiu zhenfeng
Dermatology Hospital, Southern Medical University
Outcome results
None listed