hyperthyroidism(Gall disease)
Conditions
Interventions
experimental group:Qilong Sanjie capsule
Control group:Thiamazole Tablets
Sponsors
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Age 18-65 years old (inclusive), male or female; (2) Meet the diagnostic criteria of phlegm and blood stasis syndrome of gall disease in traditional Chinese medicine; (3) Patients who meet the Western medical diagnostic criteria for Graves hyperthyroidism, are currently taking Saizhi, and have normal FT3 and FT4; (4) Patients who sign the informed consent form, voluntarily give informed consent and cooperate with the examination.
Exclusion criteria
Exclusion criteria: (1) Goiter has compression on surrounding organs or retrosternal goiter; (2) Combined with hyperthyroidism crisis; (3) Thyroiditis; (4) Patients with serious heart disease, including myocardial infarction and chronic cardiac insufficiency (NYHA grade III and IV); (5) Liver and kidney function reached one of the following indicators: A. glutamate aminotransferase (ALT) or aspartate aminotransferase (AST) > 2 times the upper limit of normal value; b. Alkaline phosphatase or total bilirubin > 2 times the upper limit of normal value; c. Urea nitrogen or blood creatinine > the upper limit of normal value; (6) Allergic constitution or possible allergy to the drug; (7) Pregnant or lactating women or those who plan to become pregnant during the trial or their spouses plan to become pregnant; (8) Those who participated in clinical research of other drugs or medical devices within 1 month before the first administration; (9) Patients with mental diseases, obvious mental disorders or epilepsy; Patients with acute diseases; Patients with current or previous malignant tumor diseases; Those without behavioral ability or cognitive ability; (10) Poor compliance or other conditions that researchers think are not suitable for inclusion (such as the estimated survival time is less than 3 months).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM syndrome score; | — |
Secondary
| Measure | Time frame |
|---|---|
| thyroid volume;Thyroid autoantibodies (TRAb, TPOAb, TgAb); | — |
Countries
China
Contacts
Public ContactJiajun Zhao
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Outcome results
None listed