Single versus multi-dose autologous Intrauterine Platelet-Rich Plasma instillation for thin endometrium in frozen embryo transfer Cycles

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300071473

Enrollment

Unknown

Registered

2023-05-16

Start date

2023-06-01

Completion date

Unknown

Last updated

2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thin endometrium

Interventions

Single perfusion group:Single Platelet-Rich Plasma Instillation

Two-perfusion group:Two Platelet-Rich Plasma Instillation

Eligibility

Sex/Gender

Female

Age

25 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) age younger than 40 years old; (2) with cancellation history of embryo transfer due to thin endometrium (<7 mm) in hormone replacement therapy (HRT) cycles; (3) no obvious intrauterine adhesion in the diagnostic hysteros-copy; (4) no submucosal uterine myoma or endometrial polyps; (5) no history of hematological disorders (e.g, leukopenia,thrombasthenia et al); (6) have at least 1 frozen good-quality blastocyst-stage embryos.

Exclusion criteria

Exclusion criteria: Patients were excluded if she had a history of pelvic cancer,severe endometriosis, and adenomyosis.

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate;abortion rate;abortion rate;	—

Secondary

Measure	Time frame
Endometrium;Blood flow indices;	—

Countries

China

Contacts

Public ContactKeng Feng

Yulin Maternal and Child Health Hospital

1010170995@qq.com+86 182 7719 5630

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026