Papillary thyroid carcinoma
Conditions
Interventions
Index test:droplet digital PCR, BRAFV600E mutation abundance
Gold Standard:Histological report,2015 ATA Management Guidelines with Differentiated Thyroid Cancer
Sponsors
Affililated Hangzhou First People's Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 18 to 80 years; (2)Papillary thyroid carcinoma confirmed by pathological diagnosis; (3) The paraffin specimens /FNA samples were complete and the collection purity reached the standard; (4) Patients voluntarily participated in the study after informed consent.
Exclusion criteria
Exclusion criteria: (1) Previous history of cervical radiation or secondary thyroid surgery; (2) The total amount of DNA, extraction methods and preservation conditions do not meet the requirements of the specimen; (3) Nodular goiter, follicular carcinoma or medullary carcinoma were the pathological types of non-thyroid papillary carcinoma specimens; (4) The case data is incomplete and untraceable; (5) The patient refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| biological behavior of papillary thyroid carcinoma;BRAFV600E mutation abundance; | — |
Countries
China
Contacts
Public ContactLuo Dingcun
Affililated Hangzhou First People's Hospital, Zhejiang University School of Medicine
Outcome results
None listed