Myocardial injury
Conditions
Sponsors
Shanghai Pulmonary Hospital, Tongji University
Eligibility
Sex/Gender
All
Age
45 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Age 45 or above; 2. Patients undergoing video-assisted thoracoscopic lung surgery under general anesthesia; 3. The operation is expected to last more than an hour; 4. Comply with any of the following 4 items: (1) History of coronary heart disease, including angina pectoris; (2) A history of stroke; (3) History of peripheral arterial disease; (4) Any 2 of the following 8 items: 1) Emergency surgery; 2) Current or former daily smoker; 3) High blood pressure; 4) diabetes that needs treatment; 5) History of cerebral ischemia; 6) Plasma creatinine >175µM; 7) Age 70 or above; 8) History of congestive heart failure.
Exclusion criteria
Exclusion criteria: 1. Coagulation dysfunction; 2. Local skin infection; 3. Glaucoma; 4. Thyroid disease; 5. Cardiac excitation conduction abnormalities; 6. The patient is mentally disabled and unable to cooperate; 7. Pregnant woman; 8. Did not sign informed consent before surgery, or refused to participate; 9. Allergy to the drug involved in the trial; 10. Sepsis; 11. Preoperative positive inotropic drug therapy was received; 12. Severe heart failure (defined as ejection fraction <30%).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative myocardial injury; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative myocardial markers;Mortality at 30 and 60 days after surgery;Incidence of acute kidney injury;Delirium incidence;Incidence of myocardial infarction;Major adverse cardiac events (MACE) and postoperative complications;Length of stay and readmission rate;Postoperative Recovery Quality Scale; | — |
Countries
China
Contacts
Public ContactHong Shi
Shanghai Pulmonary Hospital, Tongji University
Outcome results
None listed