Elective short pediatric surgery under general anesthesia
Conditions
Interventions
Sponsors
Affiliated Hospital of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Children undergoing elective short operation under general anesthesia (operation time <=90min); 2. ASA II-III; 3. Age 2-6 years old.
Exclusion criteria
Exclusion criteria: 1. known allergy to esketamine or dexmedetomidine; 2. Families with neurological and psychiatric diseases; 3. Combined with cardiovascular or pulmonary disease; 4. Complicated with hepatorenal insufficiency; 5. Increased intracranial pressure or ocular pressure; 6. History of hyperthyroidism; 7. Long-term use of sedative or analgesic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Esketamine dosage;Dexmedetomidine dosage;Median effective dose;Modified Observer’s Assessment of Alertness/Sedation Scale,MOAA/S;the parental separation anxiety scale,PSAS;Adverse reaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of onset of sedation;Awakening time ;Duration of stay in PACU;Duration of operation;Aldrete score;Heart rate ;Blood pressure ;Pulse oxygen saturation ; | — |
Countries
China
Contacts
Public ContactYating Zeng
Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College
Outcome results
None listed