Parkinson's Disease
Conditions
Interventions
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.2.1 Inclusion criteria: 1.2.1.1 Age 30-80 years old, no gender limitation; 1.2.1.2 The clinical diagnosis meets the clinically diagnosed PD patients in the Parkinson's disease diagnostic criteria established by the International Movement Disorders Society (MDS) in 2015 or the PET examination meets the imaging manifestations of typical Parkinson's disease; 1.2.1.3 Agree and cooperate with all clinical evaluations. 1.2.1.4 The patients themselves and/or their legal guardians agree to participate in this clinical trial and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1.2.2.1 Various secondary Parkinson's syndromes (including but not limited to drug-induced, poisoning, cerebrovascular disease, encephalitis, hydrocephalus, brain tumor, Wilson's disease, Huntington's chorea, Fahr's disease, etc.), Kinson-plus syndrome (multiple system atrophy, progressive supranuclear palsy, corticobasal ganglia syndrome, dementia with Lewy bodies); 1.2.2.2 Suffering from severe cognitive or mental illness; 1.2.2.3 Deep brain stimulation therapy has been performed; 1.2.2.4 Suffering from diabetes; 1.2.2.5 Clearly suffered from peripheral nerve injury in the past; 1.2.2.6 Suffering from cancer, chronic renal insufficiency, thyroid disease, autoimmune disease; 1.2.2.7 Suffering from severe cognitive impairment or psychiatric symptoms (cognitive state MMSE score <18 points), or poor physical condition to complete the examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Consistency between the ESC Composite Index and Scores on the SCOPA-AUT Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Consistency between ESC Composite Index and Blood Pressure Variability;Consistency between ESC Composite Index and Heart Rate Variability;Consistency between the ESC composite index and the CSI score;Consistency between ESC composite index and FVC scores; | — |
Countries
China
Contacts
Public ContactJingxing Zhang
Department of Neurology, Shanghai Tongji Hospital
Outcome results
None listed