Postoperative fatigue syndrome
Conditions
Interventions
Sufentanil group:Intravenous propofol 2.0 mg/kg with sufentanil 0.1 to 0.2 µg/kg for anesthesia induction.
Affentanil group:Intravenous propofol 2.0 mg/kg with afentanil 7.5 to 10 µg/kg for anesthesia induction.
Sponsors
The Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients of any gender who undergo elective gastrointestinal endoscopy with sedation; 2. Age >= 18 years; 3. Voluntary participation in research while signing informed consent.
Exclusion criteria
Exclusion criteria: 1. ASA classification >= IV; 2. BMI >=30kg/m2 3. Previous history of heart failure or EF<50%, cerebrovascular lesion sequelae, severe ventilation dysfunction, liver cirrhosis decompensation, chronic renal failure; 4. Patients with chronic pain or recent use of analgesic medications 5. pregnant or lactating patients; 6. Patients allergic to the study drug; 7. Mentally abnormalities or alcohol drug abusers; 8. History of gastrointestinal surgery; 9. Communication impediments and inability to properly understand the investigator's inquiries; 10. Disagree to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fatigue score; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of sleep;physical recovery score;Intraoperative consumption of propofol;Duration of surgery;Blood pressure, heart rate and SpO2, during examination;The number of movements during the examination;Endoscopist satisfaction score;Patient satisfaction score;the incidence and duration of adverse events;duration of anesthesia;recovery time; | — |
Countries
China
Contacts
Public ContactYun Wu
The Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed