Endotracheal intubation and extubation under general anesthesia in neonates
Conditions
Interventions
HFNC extubation group:Nasal high-flow oxygen therapy during extubation
HFNC intubation group:Nasal high-flow oxygen therapy during intubation
Conventional oxygen intubation group:Routine oxygen during intubation
Conventional oxygen extubation group:Routine oxygen during extubation
Sponsors
Zhengzhou University Third Hospital and Henan Province Women and Children's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: Vaginal birth, single birth, live birth. Apgar score of 1 at birth > 7, no history of birth asphyxia, no history of medical and surgical diseases and complications, etc.
Exclusion criteria
Exclusion criteria: Nasal catheterization, emergency intubation, pre-intubation heart rate less than 120 beats per minute, contraindications to high-flow therapy (eg, congenital nasal malformations, congenital diaphragmatic hernias, or abdominal wall defects), cyanotic congenital heart disease, heart disease, and other organic diseases. Children with acute and critical illness, those with obvious physical defects, mental illness or coma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Minimum SpO2 at intubation;First intubation success rate;Incidence of hypoxemia (SpO2<90%) after extubation;After extubation, laryngospasm and choking appear; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of intubation attempts;Cumulative time for all intubations;Intubate again after extubation;Out of the operating room time; | — |
Countries
China
Contacts
Public ContactWang Yuxia
The Third Affiliated Hospital of Zhengzhou University
Outcome results
None listed