Recurrence of stones after ERCP lithotomy
Conditions
Interventions
Exposed group (Conventional treatment +Take taurine ursodeoxycholic acid capsule):None
Non-exposed group (Conventional treatment + Blank control):None
Sponsors
The First Affiliated Hospital of Naval Medical University (Shanghai Changhai Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Subjects must meet all of the following inclusion criteria to be enrolled in this study: 1. Age 18-75 (including boundary value), gender is not limited. 2. Imaging examination diagnosed primary choledocholithiasis, and ERCP lithotomy was performed, and no residual choledocholithiasis was found in the common bile duct after surgery. 3. The subject expressed informed consent, volunteered to be tested, signed informed consent, and agreed to participate in all visits and examinations as required by the test protocol.
Exclusion criteria
Exclusion criteria: Subject will be excluded if any of the following: 1. Complicated with serious diseases of the heart, brain, lung, liver or kidney, malignant tumor or mental illness, or known or confirmed active ulcers or duodenal ulcers, acute cholecystitis and cholangitis, obstruction of the biliary tract (common bile duct or gallbladder duct), recurrent biliary colic attacks, calcification or radiopaque gallstones, impaired gallbladder motor function, Or other conditions deemed unsuitable for participation in the clinical trial by the investigator; 2. Pregnant or lactating women; 3.Allergic to any ingredient contained in tauroursodeoxycholic acid capsules, or allergic constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of stone 1 year after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stone recurrence rate at 24 weekends after surgery;Changes of blood lipid levels compared with postoperative baseline at 4, 12, 24, 36 and 48 weeks after surgery;Changes in liver function from baseline at 4, 12, 24, 36, 48 weeks after surgery; | — |
Countries
the People's Republic of China
Contacts
Public ContactZhaoshen Li
The First Affiliated Hospital of Naval Medical University (Shanghai Changhai Hospital)
Outcome results
None listed