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To explore the central regulatory mechanism of iTBS on poststroke dysphagia based on multimodal connectomic techniques

To explore the central regulatory mechanism of iTBS on poststroke dysphagia based on multimodal connectomic techniques

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071393
Enrollment
Unknown
Registered
2023-05-15
Start date
2023-05-15
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysphagia after stroke

Interventions

experimental group:Rehabilitation therapy + iTBS stimulation
control group:Rehabilitation therapy + sham iTBS stimulation

Sponsors

Shandong Third provincial hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: The diagnosis of stroke was in line with the criteria adopted by the Fourth National Conference on Cerebrovascular Diseases, and all were confirmed by head CT and MRI. (2) First onset, course of disease 2 weeks to 6 months; (3) All had dysphagia disorders manifested as different degrees of drinking water choking cough. Choking, prolonged eating time, swallowing difficulty, etc., the VFSS score was moderate to severe; (3) no lung disease; (4) Age 40-80 years old; (5) Clear consciousness, cooperative ability, no serious cognitive, visual and hearing impairment or mental illness, MMSE score more than 24 points; (6) Informed consent shall be approved by the Ethics Committee

Exclusion criteria

Exclusion criteria: Excluding severe liver, kidney, hematologic diseases and endocrine system primary diseases (2) mental disorders or low intellectual and cognitive function (3) previous or concurrent other diseases affecting swallowing function, such as head and neck tumors, esophageal tumors, myasthenia gravis, etc.; (4) There are contraindications for iTBS treatment and contraindications for MRI. (5) Observers who did not complete the treatment according to the requirements for various reasons, whose observation records were incomplete, or who received other treatments during the treatment

Design outcomes

Primary

MeasureTime frame
VFSS scals;SSA scals;Brain MRI;

Countries

China

Contacts

Public ContactShanshan Wang

Shandong Third provincial hospital

35111972@qq.com+86 156 6831 9429

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026