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The effect of different artificial assisted cough stimulation techniques on cough function in brainstem stroke patients

The effect of different artificial assisted cough stimulation techniques on cough function in brainstem stroke patients

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071388
Enrollment
Unknown
Registered
2023-05-13
Start date
2023-05-12
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Experimental group 1:Stimulate the base of the tongue
Experimental group 2:stimulation of the trachea
Experimental group 3:stimulation of diaphragm

Sponsors

Beijing Xiaotangshan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: ?1.Conforming to the diagnostic and classification criteria for stroke injury in the 2015 edition of the Chinese Classification of Cerebrovascular Diseases, confirmed as brainstem injury through head CT or MRI examination, with the first onset and a course of = 3 months; 2. Patients are able to understand and follow simple oral instructions (MMSE score: above middle school>24 points, primary school>20 points, illiteracy>17 points); 3.Between the ages of 40 and 75; 4. First onset within 3 months; 5. Cough peak flow rate<270L/min; 6.The patient and their family members are willing to receive bedside assisted cough training and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Individuals with a history of epilepsy and severe failure of important organs such as the heart, lungs, liver, and kidneys; 2. Patients with bronchopleural fistula, pneumothorax, pulmonary hemorrhage, and hemoptysis; 3. The patient and their family members do not receive treatment; 4. There are other neurological, respiratory, and orthopedic diseases that affect cough function, such as phrenic nerve injury, asthma, rib fractures and Severe osteoporosis.

Design outcomes

Primary

MeasureTime frame
Cough Peak Expiratory Flow;

Secondary

MeasureTime frame
Bilateral diaphragmatic thickness;Bilateral diaphragm thickness fraction;Bilateral diaphragm mobility;forced vital capacity;FEV1%;FEV1/FVC;arterial blood gas analysis;semiquantitative cough intensity score;Sputum viscosity;

Countries

China

Contacts

Public ContactWu Liang

Beijing Xiaotangshan Hospital

1972wuliang@sina.com+86 152 1087 8101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026