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Clinical efficacy of atorvastatin combined with conbercept in the treatment of patients with retinal vein occlusion macular edema and carotid artery plaques

Clinical efficacy of atorvastatin combined with conbercept in the treatment of patients with retinal vein occlusion macular edema and carotid artery plaques

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071359
Enrollment
Unknown
Registered
2023-05-12
Start date
2023-07-01
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

retinal vein occlusion

Interventions

Experimental group:atorvastatin combined with conbercept

Sponsors

Nanjing Lishui People's hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: ? The patient is aged between 45 and 75 years old, and their visual acuity suddenly decreases within 2 weeks (best corrected visual acuity<0.5). ? According to outpatient dilated pupil fundus fluorescence angiography (FFA), there is delayed venous filling in the early stage of angiography, and fluorescein leakage in the macular area in the late stage of angiography, And the frequency domain optical coherence tomography (SD-OCT) showed a central subfield retinal thickness (CSFT) value greater than 250um, indicating a diagnosis of RVO-ME patients; ? Patients with carotid artery plaques confirmed by carotid artery Doppler ultrasound examination and stenosis<50%.

Exclusion criteria

Exclusion criteria: ? Patients with severe cataracts, macular membrane, optic neuropathy, glaucoma, and uveitis; ? Patients with macular edema secondary to senile macular degeneration and diabetes retinopathy; ? Patients with a history of intravitreal injection, retinal surgery, or laser photocoagulation in the past; ? Patients who have taken lipid-lowering drugs within the past month; ? Patients with severe cardiovascular, cerebrovascular, and liver and kidney dysfunction.

Design outcomes

Primary

MeasureTime frame
best corrected visual acuity;central subfield foveal thickness;injection number;Carotid artery intimal thickness;

Countries

China

Contacts

Public ContactYao Bangtao

Nanjing Lishui People's hospital

yaobamtao_njmu@163.com+86 138 0519 8257

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026