PONV
Conditions
Interventions
Propofol-sufentanil (Control group):Patients in the control group received general anesthesia with sufentanil 0.1µg/kg combined with propofol during operation
Simple propofol anesthesia group (Experimental group):Patients in the Experimental group were given general anesthesia with propofol
Sponsors
Hebei General Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria All 182 enrolled subjects had indications for endoscopy and anesthesia and met the following criteria: ? PONV high-risk patients who underwent painless endoscopy (Apfel risk summary score > 1 was considered as high risk); ? Age 18-50 years old; ?ASA grade I or II.
Exclusion criteria
Exclusion criteria: Exclusion criteria ? Allergic history of narcotic drugs and the use of benzodiazepines or opiates within 3 months ? pregnancy or lactation ? significant dysfunction of heart, lung, liver and kidney before surgery; ? serious neurological and mental disorders can not express themselves correctly.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PONV socer;Patient satisfaction with anesthesia;Incidence of postoperative adverse reactions and intraoperative adverse events in patients;Patient's recovery room (PACU) stay time; | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of propofol used in the patient's intraoperative anesthesia;Duration of anesthesia (the time between the cessation of initial administration and the patient's response to eye opening and exhalation);Hemodynamic changes (SBP, DBP, MAP, and HR) at 5 time points during surgery.; | — |
Countries
China
Contacts
Public ContactZhu Xichun
Hebei General Hospital of Shijiazhuang, Hebei Province
Outcome results
None listed