tracheal intubation response
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.undergoing elective tracheal intubation surgery under general anesthesia, 2.18-60 years old, 3.BMI 18.5-25.0 kg/m2, 4.ASA I-II grade, 5.signe informed consent form.
Exclusion criteria
Exclusion criteria: 1.Allergies to anesthetic drugs such as remidazolam; 2.After entering the room, in a quiet state, SBP = 160mmHg, DBP = 100mmHg, MAP = 120mmHg, HR = 100 times/minute; 3.Preoperative evaluation as difficult airway; 4.Severe heart, lung, kidney, and metabolic diseases; 5 Prior to surgery, there was a history of abuse of opioids or other sedatives.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Median effective dose of remimazolam; | — |
Secondary
| Measure | Time frame |
|---|---|
| HR;the consciousness disappear time;time of BIS < 60; | — |
Countries
China
Contacts
Department of Anesthesiology, Chaohu Hospital Affiliated to Anhui Medical University