Depression
Conditions
Interventions
Observation group:Yi Shu psychodrama treatment
Control group:first-line antidepressant (escitalopram oxalate) treatment
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria for single-phase depressive episodes in the tenth edition of the International Classification of Diseases (ICD-10), with a score of 5<BDI-13<16 (2) Junior high school or above education level (3) Never taken antidepressants before or withdrawal of more than a month (4) Ability to cooperate with pre-enrollment physical examinations, understand and cooperate with questionnaire filling, cranial fMRI, etc. (5)18.5=BMI<24kg/m2 (6) Voluntary participation and signing the consent inform
Exclusion criteria
Exclusion criteria: (1) Organic brain diseases and imaging data that are not qualified (2) Merging other mental illnesses, including persistent depressive episodes with psychotic symptoms, bipolar depression, post-traumatic stress disorder, and severe personality disorders (such as borderline personality) (3) Severe physical diseases, including hypertension, diabetes, coronary heart disease, thyroid disease, etc (4) Alcohol or substance dependence (5) Serious suicidal ideation, self-injurious behavior and suicide attempt (6) Electroconvulsive therapy within 6 months or other systemic psychotherapy or transcranial magnetic therapy (7) Major surgery within 3 months or history of cold and fever symptom within 2 weeks (8) Patients receiving glucocorticoid therapy (9) Pregnant or lactating women (10) Left-handedness (11) Having contraindication of MRI scanning, unable to complete MRI scanning or be alone in confined space for 1h (12) Diagnosis of other sleep disorders such as apnea syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Beck Depression Inventory-13 Item;Beck Anxiety Inventory-21 Item;Automatic Thoughts Questionnaire;Connor Davidson Resilience Scale;Self-Esteem Scale;Cognitive Emotion Regulation Questionnaire Chinese Version ;Simplified Coping Style Questionnaire;Temporal Experience of Pleasure Scale;adult attachment scale;Pittsburgh sleep quality index; | — |
Countries
China
Contacts
Public ContactHua Hu
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed