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A randomized, controlled, single-blind, multicenter clinical trial to evaluate the efficacy and safety of a real-time single sperm selection grading system for intracytoplasmic sperm injection

A randomized, controlled, single-blind, multicenter clinical trial to evaluate the efficacy and safety of a real-time single sperm selection grading system for intracytoplasmic sperm injection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071335
Enrollment
Unknown
Registered
2023-05-11
Start date
2023-05-20
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who meet the ICSI indications

Interventions

Experimental Group:Selecting sperm using the Real Time Single Sperm Selection and Grading System (RSSGS)
Control Group:Selecting sperm manually

Sponsors

The Reproductive and Genetic Hospital of CITIC-Xiangya
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 43 Years

Inclusion criteria

Inclusion criteria: Female patients: 1. age = 43 years; 2. in an ICSI cycle; 3. the number of MII oocytes obtained from egg retrieval = 6; 4. the subject agreed to culture all embryos to the blastocyst stage; 5. Subjects read and signed the informed consent form. Male patients: 1. subject's semen collected by normal ejaculation; 2. in an ICSI cycle; 3. the subject read and signed the informed consent form.

Exclusion criteria

Exclusion criteria: Female patients 1. Subjects' oocytes are frozen oocytes or in vitro matured (IVM) oocytes. Male patients: 2. Subjects' sperm are either frozen sperm, surgically retrieved sperm (including sperm retrieved from the epididymis or testes), or from patients with extreme oligospermia and oligospermia.

Design outcomes

Primary

MeasureTime frame
Blastocyst Formation Rate;

Secondary

MeasureTime frame
Fertilization Rate;Implantation Rate;Clinical Pregnancy Rate;Ongoing Pregnancy Rate;

Countries

China

Contacts

Public ContactLin Ge

The Reproductive and Genetic Hospital of CITIC-Xiangya

linggf@hotmail.com+86 131 8705 7355

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026