knee osteoarthritis
Conditions
Interventions
actual-rTMS group :The true stimulation group received a real high-frequency rTMS intervention with the coil tangential to the scalp and conventional treatments such as acupuncture, physiotherapy, and
Sham-rTMS group :Sham-rTMS + conventional treatments
Sponsors
The First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? Age 40 years and above, regardless of gender; ?Patients diagnosed with knee osteoarthritis according to the criteria of "China Osteoarthritis Treatment Guidelines (2021 Edition)", "Osteoarthritis Treatment Guidelines (2018 Edition)"; That is, patients who meet the following criteria 1+ (any two of 2, 3, 4, 5), 1) recurrent knee pain within the last 1 month; 2) X-ray (standing or weight-bearing position) showing joint space narrowing, subchondral osteosclerosis and or cystic lesions; 3) age = 50 years; 4) morning stiffness = 30 min; 5) bone friction sound (sensation) during activity; ? those with Kellgren-Lawrence grading scale I-III for knee osteoarthritis joint degeneration; ? patients with a mean pain score of VAS = 3 in the past 1 week; ? Subjects with normal lower extremity force lines; ?Patients agreed and signed the informed consent form.
Exclusion criteria
Exclusion criteria: ? those with confirmed diagnosis of rheumatoid arthritis, gout, severe osteoporosis, tuberculosis, tumors; ? patients who have previously taken long-term drugs related to the treatment of osteoarthritis of the knee or who have undergone intra-articular injection therapy within 6 months; ? patients with combined severe heart, brain, kidney or lung dysfunction or mental illnesses that are not conducive to rehabilitation training or magnetic therapy ? patients with stroke, brain surgery, cognitive impairment, alcohol or drug abuse or other conditions or symptoms that are likely to prevent completion of the program; ? patients with a history of epilepsy, metal built into the skull, high intracranial pressure, implanted pacemakers, or other contraindications to transcranial magnetic stimulation; ? patients with a history of artificial knee arthroplasty or non-arthroscopic surgery; ? patients with poor compliance and unable to cooperate to complete the treatment; ? those who are unable to sign the informed consent form or have participated in other research projects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee Dysfunction Score;Pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee joint mobility;oxyhemoglobin (HbO), reduced hemoglobin (rHb), and total hemoglobin;Quality of life;Anxiety score; | — |
Countries
China
Contacts
Public ContactMaoyuan Wang
The First Affiliated Hospital of Gannan Medical University
Outcome results
None listed