brain disease
Conditions
Interventions
Group 1:Routine rehabilitation + Transcranial magnetic stimulation (1HZ)
Group 2:Routine rehabilitation + Transcranial magnetic stimulation (10HZ)
Group 3:Routine rehabilitation + Transcranial magnetic stimulation (0HZ)
Sponsors
Shandong Third Provincial Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: According to Wang Zhongcheng Neurosurgery, the formation mechanism of coma with craniocerebral injury and the time to promote recovery were used to establish diagnostic criteria: (1) There was an obvious history of craniocerebral injury and cerebral hemorrhage, and some patients had a history of cerebral hernia; ? Patients with severe craniocerebral injury who were confirmed by head CT or MRI and clinical examination (such as pupil observation) and admitted to hospital within 24h after injury; (3) Coma GCS score was used, coma lasted for more than 6 hours after injury or consciousness deteriorated within 24 hours after injury for more than 6 hours again; ? Under 70 years old; ? The survival time was > 72h and the vital signs were stable. There was no active intracranial hemorrhage after 72h observation. ? All of them were hospitalized cases in the intensive rehabilitation Department of our hospital with medical records; ? The patient's family members gave informed consent to treatment, and signed informed consent. Patients meeting the above diagnostic criteria can be included in the treatment observation.
Exclusion criteria
Exclusion criteria: ? Patients with serious primary diseases of heart, cerebrovascular, liver and kidney, or other serious primary craniocerebral diseases; ? Severe irreversible brain stem injury, showing a serious state of decerebral tetania, and the course of disease more than 60 days; ? Severe combined injury with other important organs and limbs combined injury, and affect the brain awakening disorder; ? In patients with contraindications for MRI examination, such as metal foreign bodies or implants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Near infrared functional brain imaging;Functional Magnetic Resonance Imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Coma Recovery Scale Rehabiration, CRS-R; | — |
Countries
china
Contacts
Public ContactLu Wei
Shandong Third Provincial Hospital
Outcome results
None listed