early postoperative recovery quality
Conditions
Interventions
Esketamine group (Group E):Esketamine group (Group E) analgesic pump plan: Esketamine hydrochloride injection 0.5mg/kg+Dizosin injection 5mg/10kg+Dexmetomidine hydrochloride injection 1.5 µ G/kg+flurb
Control group (Group C):Control group (Group C) analgesic pump plan: Dizosin injection 5mg/10kg+Dexmetomidine hydrochloride injection 1.5 µ G/kg+flurbiprofen axetil injection. The background infusion
Sponsors
The Fourth Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Select patients with gastrointestinal tumors who undergo elective surgical treatment in our hospital; 2) American anesthesiologists (ASA) are classified as Grade I-III; 3) Age 18-65 years old, body mass index (BMI) 18.5-25kg/m ²; 4) Agree to participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Emergency surgery; 2) Contraindications for the use of ketamine: patients with aneurysmal vascular disease or arteriovenous malformations, history of cerebral hemorrhage, history of glaucoma, untreated or insufficiently treated hyperthyroidism, and patients with severe risk of hypertension or elevated intracranial pressure; 3) Allergy to Esketamine; 4) Unable to cooperate with research due to mental disorders or mental illnesses; 5) Transferring to ICU after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hospital anxiety and depression scale;QoR-15; | — |
Countries
China
Contacts
Public ContactHuaqin Liu
The Fourth Hospital of Hebei Medical University
Outcome results
None listed