peptic ulcer bleeding
Conditions
Interventions
Experimental group:Medical Glue Embolization treatment
Control group:Treatment of peptic ulcer bleeding with one or two or more standard combination regiments includes:
1. Endoscopic drug injection treatment
2. Endoscopic digestive endoscopic hemostatic c
Sponsors
Affiliated Hospital of Zunyi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years, no gender limit; Hematemesis and/or black stool, blood loss such as dizziness, sweating, palpitation, shock, etc.; 2. Peptic ulcer with acute bleeding caused by various causes can be characterized by jet bleeding (Forrest Ia), active bleeding (Forrest Ib), and naked blood vessel diameter >=2mm (Forrest IIa grade) under endoscopy, as long as one of them is satisfied; 3. High risk of rebleeding (defined as Blatchford score >=6); 4. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with high suspicion of malignant ulcer transformation; 2. Patients with other tumors; 3. Patients with varicose bleeding from portal hypertension; 4. Severe cardiopulmonary and cerebrovascular diseases, including acute myocardial infarction, severe conduction block and heart failure; Including severe lung infection, severe emphysema, pulmonary heart disease and respiratory failure; Including severe cerebral ischemia, severe cerebral infarction, etc. Suffering from other end-stage diseases; Patients who cannot accept or cooperate with endoscopic therapy; 5. Patients with peptic ulcer perforation requiring surgery; 6. Severe liver and kidney insufficiency; 7. The researcher considers that the candidate is not suitable; 8. Pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of hemostasis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Retreatment intervention; | — |
Countries
China
Contacts
Public ContactTuo Biguang
Affiliated Hospital of Zunyi Medical University
Outcome results
None listed