Post-stroke dysphagia, PSD
Conditions
Interventions
acupuncture group:acupuncture
sham acupuncture group:sham acupuncture
waiting-list group:no acupuncture treatment, receiving compensation acupuncture for two weeks after the end of the observation cycle
healthy control group:none
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for ischemic stroke patients with pseudobulbar paralysis: (1) Meet the diagnostic criteria for acute ischemic stroke in the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018 and the diagnostic criteria for dysphagia disorders (the diagnostic criteria for the Treatment of Stroke Patients: Identification and Treatment of dysphagia in the National Clinical Guidelines for Stroke written by the Scottish College Guidelines Collaboration Group); (2) Aged 18-80 years; (3) Functional oral feeding (FOIS) score 2-5; (4) 30 days <= duration <=160 days; (5) The infarct was located in the cerebral cortex; (6) The patient or legal representative gives informed consent and signs the informed consent. 2. Inclusion criteria for health controls: (1) From community recruitment; (2) Gender and age matched with the experimental group; (3) No history of stroke, diabetes, hypertension, hyperlipidemia, coronary heart disease, etc.; (4) No history of smoking or drinking; (5) The National Institute of Health Stroke Scale (NHISS) assessed the degree of neurological impairment <=1 score; (6) No responsible lesions were determined by brain CT or MRI.
Exclusion criteria
Exclusion criteria: Exclusion criteria for ischemic stroke patients with pseudobulbar paralysis: 1. Patients with dysphagia disorder before the onset of the disease; 2. Suffering from other life-threatening serious diseases with an expected survival time of less than 3 months; 3. Unable to complete the study due to mental illness, cognitive or emotional disorders; 4. Patients with severe needle fainting intolerance; 5. Unable to complete the swallowing function assessment; 6. Patients who are pregnant, planning pregnancy or breastfeeding; 7. Patients who have participated in other drug clinical trials in the past 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Oral Intake Scale (FOIS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional connection (FC);Regional homogeneity (ReHo);Amplitude of low (ALFF);Standardized Swallowing Assessment (SSA);Body mass index (BMI);Edinburgh Handedness Inventory(EHI);Self-Rating Anxiety Scale (SAS);Self-Rating Depression Scale (SDS);Massachusetts Hospital Acupuncture Sensory Scale (MASS); | — |
Countries
China
Contacts
Public ContactFan Xiaonong
The First Affiliated Hospital of Tianjin University of Chinese Medicine
Outcome results
None listed