atopic dermatitis
Conditions
Interventions
head and neck dermatitis treatment group :Traditional Chinese medicine oil for external use
head and neck dermatitis control group:Camellia oil, the substrate of topical Chinese medicine oil
ordinary AD control group:None
healthy control group:None
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine (The Second Clinical Medical College of Guangzhou University of Traditional Chinese Medicine)
Eligibility
Sex/Gender
All
Age
12 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria of head and neck AD group: (1) The diagnostic criteria for atopic dermatitis were met by Williams(1994). (2) Aged 12-65 years, gender is not limited. (3) For patients with erythema, edema, pruritus, desquamation and other symptoms during acute onset of head and neck AD, head and neck lesions were >= 10% of the entire head and neck area, and the researchers IGA score was >=2 points. (4) Sign a written informed consent (minor subjects need to obtain the informed consent and signature of the child and guardian at the same time). 2. General AD group inclusion criteria: (1) The diagnostic criteria for atopic dermatitis were met by Williams(1994). (2) Aged 12-65 years, gender is not limited. (3) No skin lesions on the head and neck. (4) Sign a written informed consent (minor subjects need to obtain the informed consent and signature of the child and guardian at the same time). 3. Inclusion criteria of healthy control group: (1) Aged 12-65 years, gender is not limited, Chinese healthy population. (2) Sign a written informed consent (minor subjects need to obtain the informed consent and signature of the child and guardian at the same time).
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for head and neck AD group and common AD group: (1) Patients with other skin diseases requiring treatment. (2) Patients who have received immunosuppressants, glucocorticoids, antibiotics and other treatments within the past 1 week (including systemic and local drugs). (3) Patients with other major underlying diseases such as heart and lung; People with mental illness. (4) Patients who are not suitable for this treatment, such as those who are known to be allergic to drugs related to the drug in this study (such as in vitro cultured bezoar and camellia oil). Chronic skin lesions, such as lichenosis, hypertrophy. (5) More acute skin exudation. 2. Exclusion criteria for healthy control group: (1) Combined with infectious diseases and other allergic diseases, such as asthma, allergic rhinitis, hay fever, allergic conjunctivitis, urticaria and so on. (2) Complicated with other basic diseases such as heart, brain, lung and kidney.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Head and Neck Eczema Area and Severity Index (EASI Score);Visual Analogue Scale of Itch and Insomnia;Patient-Oriented Eczema Measure, POEM;Dermatology Life Quality Index, DLQI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Physiological parameters of skin; | — |
Countries
China
Contacts
Public ContactLin Ying
Guangdong Provincial Hospital of Traditional Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed