keloid and hyperplastic scar
Conditions
Interventions
experimental group:Carrier-free 5-fluorouracil+resection+radiotherapy
control group 1:Pure 5-fluorouracil + resection+radiotherapy
control group 2:Resection+radiotherapy
Sponsors
The Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. The course of disease is more than half a year; Scar is stable; It was confirmed that it was consistent with the morphological characteristics of hypertrophic scar and the diagnostic criteria of hypertrophic scar. For patients diagnosed with keloid, the scope of scar hyperplasia is beyond the original injured area and shows tumor growth, surgical treatment is proposed; 2. Aged range from 20 to 50 years; 3. This study was approved by the ethics committee of the hospital, and patients were informed of the possible advantages and disadvantages before and after medication in detail. Patients and their families voluntarily chose the treatment plan and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients planning to give birth in the near future, or women who are pregnant and breastfeeding; 2. Postoperative or previous injections to treat recurrent scars; 3. Signs of infection in scar; 4. Patients did not accept the treatment regimen set by the study; 5. The patient has systemic diseases that are not suitable for surgical resection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gene sequencing; | — |
Countries
China
Contacts
Public ContactLi Ying
Affiliated Hospital of Southwest Medical University
Outcome results
None listed