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Comparison of different bolus delivery speeds of programmed intermittent epidural bolus combined with dural puncture epidural block during labor analgesia:a randomized controlled study

Comparison of different bolus delivery speeds of programmed intermittent epidural bolus combined with dural puncture epidural block during labor analgesia:a randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300071206
Enrollment
Unknown
Registered
2023-05-08
Start date
2023-06-01
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain of labor

Interventions

Low speed group:120ml/h (low speed)
Medium speed group:240ml/h (medium speed)
High speed group:360ml/h (high speed)

Sponsors

Shanghai First Maternity and Infant Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) Class I to II healthy full-term primipara, aged 20 to 40 years; 2. Single pregnancy, cephalic position; 3. Regular contractions, cervical dilation of 2~5cm; 4. Report a baseline pain score of >5 on the Pain Numerical Rating Scale (NRS).

Exclusion criteria

Exclusion criteria: 1. Body mass index (BMI) >35kg/m^2; 2. Complicated with cardiac and brain dysfunction; 3. Preeclampsia, history of drug abuse; 4. Medication for chronic pain, contraindications for intraspinal puncture; 5. Conditions that increase the risk of caesarean section (i.e. placenta previa, uterine abnormalities, or surgical history), fetal abnormalities. Patients were also excluded if delivery occurred within 1 hour of intraperitoneal analgesia.

Design outcomes

Primary

MeasureTime frame
the highest upper sensory block level to ice during the study period;

Secondary

MeasureTime frame
the presence of a sensory block level to ice =T4 for a patient at any time;hourly sensory block levels;hourly degree of motor block;hourly pain scores ;the number of patient controlled epidural analgesia demand boluses;ropivacaine consumption per hour;maternal satisfactory of labor analgesia;incidence of hypotension;incidence of other side effects;

Countries

China

Contacts

Public ContactXu Zhendong

Shanghai First Maternity and Infant Hospital

18255354282@163.com+86 176 2195 9779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026