chronic obstructive pulmonary disease (COPD)
Conditions
Interventions
PSV group:Pressure support ventilation will be administered
NAVA group:NAVA ventilation will be administered
NAVA+EDP group:NAVA ventilation and EDP will be administered
Sponsors
The First People's Hospital of Lianyungang City
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients admitted to ICU with AECOPD requiring invasive mechanical ventilation; 2. Aged > 18 years; 3. BMI 18-24 Kg/m^2; 4. Informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with neuromuscular disease; 2. Patients with esophageal stenosis, perforation, esophageal and gastric varices bleeding; 3. Patients with thoracic malformation and diaphragmatic hernia; 4. Patients with severe coagulation disorder before; 5. Patients with multiple organ failure; 6. Pregnancy, tumor terminal stage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diaphragmatic potential, EAdi;espiratory rate (RR);oxygenation index (OI);tidal volume (Vt);pulmonary static compliance;plateau pressure;airway pressure;intrinsic positive end-expiratory pressure (PEEPi);diaphragmatic excursion (DE);diaphragm thickening fraction (DTF); | — |
Countries
China
Contacts
Public ContactKang Xiuwen
The First People's Hospital of Lianyungang City
Outcome results
None listed