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Comparison of one-stage and two-stage surgery for synchronous bilateral multiple primary non-small cell lung cancer: a prospective, non-randomized controlled clinical trial

Surgical strategy selection of synchronous bilateral multiple primary non-small cell lung cancer

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300071198
Enrollment
Unknown
Registered
2023-05-08
Start date
2023-05-09
Completion date
Unknown
Last updated
2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

One-stage group (Bilateral pulmonary lesions resected in one-stage by minimally invasive surgery):N/A
Two-stage group (Bilateral pulmonary lesions resected in two-stage by minimally invasive surgery):N/A
Retrospective group (Underwent one-stage or two-stage surgery for bilateral pulmonary lesions in our department before):N/A

Sponsors

Department of Thoracic Surgery, China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. 18 to 80 years old; 2. Surgical intervention is needed for bilateral pulmonary lesions according to the guidelines for the diagnosis and treatment of pulmonary nodules, clinical stage T1-2N0-1M0; 3. ASA stage: I-III; 4. Indications for minimally invasive surgery (Thoracoscopic or robotic surgery); 5. Normal preoperative evaluation; 6. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Underwent adjuvant therapy before surgery; 2. Pathologically confirmed benign; 3. History of other malignant tumor; 4. Small cell lung cancer; 5. Pathologically confirmed metastatic tumor.

Design outcomes

Primary

MeasureTime frame
5-year overall survival;

Secondary

MeasureTime frame
5-year disease free survival;3-year overall survival;3-year disease free survival;Complications rate;30-day mobility;Pain score;Quality of life score;Surgical time;Blood loss in the operation;Duration of chest tube;Length of stay;

Countries

China

Contacts

Public ContactHan Yu

China-Japan Friendship Hospital

18818271551@163.com+86 18818271551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026