premature infant
Conditions
Interventions
Control group:a fixed FiO 2 is set. When the child's SpO 2 is above 90% and 94% or less, and the blood oxygen alarm, then the medical staff will manually adjust the oxygen concentration to maintain th
Experimental group:Turn on the intelligent oxygen control function of the ventilator, FIO2 automatic adjustment of the initial interval of 0.25% . Twenty-one-zero. 40. The control range of SpO2 is bet
Sponsors
Qujing Maternal and Child Health Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ?Gestational age 30 to 34 weeks, weight less than 1800g ? Meet the N RDS diagnostic criteria of Practical Neonatology (5th edition), and the clinical diagnosis is N RDS (combined with clinical symptoms and chest X-ray findings) ? Those who are directly given non-invasive ventilator assisted ventilation at birth, or who have undergone endotracheal intubation or have undergone short endotracheal intubation for emergency resuscitation, and who are given non-invasive ventilator assisted breathing after evacuation of invasive ventilator can be enrolled ?Parents signed the informed consent form ?Sex is not limited
Exclusion criteria
Exclusion criteria: ? Abnormal development of the respiratory system, such as nasal development malformation, cleft palate, minor jaw malformation syndrome, posterior nostrise atresia, esophageal-tracheal leakage, congenital diaphragmatic hernia, etc.; progressive respiratory failure can not maintain oxygenation, severe BPD children. ?Unstable cardiovascular system, such as pulmonary arterial hypertension, hypotension, and cardiac insufficiency; ?Respiratory drive instability, such as central apnea or no spontaneous breathing; ?Emphysema, pneumothorax, gastrointestinal bleeding, severe abdominal distension, NEC, local damage (nasal mucosa, mouth, and face); ?Children with disease aggravation requiring mechanical ventilation and maintenance for intubation; ?Abandof treatment, automatic discharge and death of children ?Parents refused to sign the treatment consent form ?Children are participating in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the proportion of the target SpO 2 range of 90-94%.; | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of times the oxygen concentration is manually adjusted.;Length of hospitalization;retinopathy; | — |
Countries
China
Contacts
Public Contactli chuanfeng
Qujing Maternal and Child Health Hospital
Outcome results
None listed