The effect of inspiratory muscle training in difficult to wean patients with neuromuscular disease

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300071173

Enrollment

Unknown

Registered

2023-05-06

Start date

2023-05-08

Completion date

Unknown

Last updated

2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuromuscular Disease

Interventions

intervention group:Threshold load inspiratory muscle training and Routine pulmonary rehabilitation

control group :Routine pulmonary rehabilitation, including airway clearance, physical activity, and postural management.

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with neuromuscular disease with tracheostomy and mechanical ventilation for more than 48 hours 2. Patients with neuromuscular diseases who have been assessed by clinicians as being stable and ready to be weaned, and who cannot tolerate weaning within 24 hours

Exclusion criteria

Exclusion criteria: 1. Patients who are unconscious (GCS score less than or equal to 8 points) and unable to cooperate 2. Patients with other respiratory and circulatory diseases, including COPD, chronic heart failure, pneumothorax, severe emphysema, pulmonary hypertension, uncontrolled asthma, etc.

Design outcomes

Primary

Measure	Time frame
Successfully taken offline;Time spent successfully offline;	—

Secondary

Measure	Time frame
Maximum inspiratory pressure;Diaphragm excursion and thickness;Maximum autonomous ventilation capacity;Rapid shallow breathing index;	—

Countries

China

Contacts

Public ContactQiu Xiang

The first affiliated hospital of Fujian medical university

18120890798@163.com+86 18120890798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026